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Healthy diet decreases incidence of Gallstone disease

Healthy diet decreases incidence of Gallstone disease

According to a new study, Healthy diet may decrease the incidence of Gallstone disease.

Higher adherence to healthy dietary patterns (Dietary Approaches to Stop Hypertension [DASH],  Alternate Healthy Eating Index [AHEI-2010], alternate Mediterranean [aMed]) may lower the risk of symptomatic gallstone disease.

Results of the study published in the International Journal of Epidemiology indicates that dietary interventions with a focus on high-quality diets may decrease the incidence of gallstones.

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Janine Wirth, Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA, and colleagues conducted the study to investigate the association between three diet-quality scores corresponding to adherence to healthy dietary patterns (aMed, AHEI-2010, DASH) and the risk of symptomatic gallstone disease. 

Also Read: Bariatric surgery increases gallstone risk, study finds

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The study involved a total of  43,635 men from the Health Professionals Follow-up Study—an ongoing prospective cohort study of US health professionals. Study participants were free of symptomatic gallstone disease and diabetes and provided dietary information every 4 years from 1986 (baseline) to 2012. The aMed, AHEI-2010, and DASH scores were generated and associated with the risk of symptomatic gallstone disease using Cox proportional hazards regression.

During 716 904 person-years of follow-up, 2382 incident cases of symptomatic gallstone disease were identified.

Also Read: 4100 gallstones removed from a patient in 4 hrs intensive surgery

Key Findings:

  • All three scores were inversely associated with risk of symptomatic gallstones after adjustment for potential confounders including age, smoking, physical activity, energy and coffee intake [hazard ratios (HRs) and 95% confidence intervals (CIs)] comparing the highest with the lowest quintiles: aMed: 0.66 (0.57–0.77), AHEI-2010: 0.64 (0.56–0.74) and DASH: 0.66 (0.58–0.76)].
  • Findings were similar after additional adjustment for body mass index and after inclusion of asymptomatic cases.
  • Associations were stronger when the analysis was restricted to cases who had undergone cholecystectomy.

“In this prospective cohort of male US health professionals, higher adherence to the aMed, AHEI-2010 and DASH diets was associated with lower risk of symptomatic gallstones. Dietary recommendations focusing on high-quality diets targeting symptomatic gallstone disease may lower the incidence of this prevalent disease,” concluded the authors.

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Source: With inputs from International Journal of Epidemiology

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