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    • Wilms tumour- GOI...

    Wilms tumour- GOI Standard Treatment Guidelines

    Written by supriya kashyap kashyap Published On 2018-10-22T19:00:39+05:30  |  Updated On 22 Oct 2018 7:00 PM IST
    Wilms tumour- GOI Standard Treatment Guidelines

    Dr Anil K. D’ Cruz, Director and chief Head and Neck Services, Tata Memorial Hospital, Mumbai has prepared Standard Treatment Guidelines for Wilms tumour on behalf of Ministry of Health and Family Welfare, Government of India which has released the same.


    Wilms tumour is the most common renal malignancy in children. It predominantly affects children under 5 years of age, most commonly during the first 2 years of life. Contemporary treatment of Wilms tumour has led to an overall survival of over 85% and the emphasis is now shifting from successful treatment to reducing treatment-associated morbidity without loss of efficacy.


    Following are the major recommendations :


    Radiological report for Wilms Tumour


    Should be a contrast enhanced CT/MRI of abdomen
    Laterality: Right or Left or Bilateral disease
    Location: which pole
    Size


    Local extent:




    • Is it Completely Intra-renal location or is Perinephric spread evident

    • Renal sinus infiltration.

    • Renal vein status

    • IVC status.

    • Renal artery : comment about the abdominal origin as well, comment on accessory arteries if any

    • Infiltration of liver, pancreas, bowel, GB, or abdominal wall


    Significant ascites, Peritoneal implants
    Adenopathy: Enlarged nodes
    Metastatic disease: Lung, liver, bone or extra-abdominal nodes

    Synoptic Pathology report for a renal tumour
    Gross Examination: Received a specimen of right / left radical nephrectomy / nephrectomy/partial nephrectomy measuring -------X------X-------- cm. including perinephric fat. Hilum of the kidney shows ureter measuring --------cm along with arterial and venous stumps.
    On cutting open, the kidney measures ----------X--------X--------cm and shows a tumour measuring--------X--------X-------- cm involving---------------------------------of the kidney. Cut surface of the tumour is solid / nodular solid / solid-cystic. Areas of necrosis and hemorrhage are-----------------------. Tumour invades through the renal capsule and extends into perinephric fat grossly / doesnot invade the renal capsule. Tumour involves / does not involve the Gerotta’s ( renal )fascia.
    Renal sinus is----------------. Renal vein invasion is--------------------------------. Renal pelvis and ureter are-----------------------------. Resection end of ureter is ------------------------------- Resection end of renal vein is -----------------------------. Hilum of the kidney reveals-----------------nodes. Foci of nephroblastomatosis are not indentified / identified . A slice of the tumour is cut in a grid fashion and submitted for histopathology examination.


    Microscopy:
    Right / Left radical nephrectomy / Nephrectomy / Partial nephrectomy ,
    Post chemotherapy / History of neo-adjuvent chemotherapy unknownTriphasic
    / Biphasic / blastemal predominant / teratoid Wilm’s tumour of ------------kidney.
    -------------------------------------------------------------------------------------------------------------------------------
    -------------------------------------------------------------------------------------------------------------------------------
    ----------------------------------------------------------------------
    Favourable histology ( FH ) / unfavourable histology (UH )
    Anaplasia is absent. Focal / diffuse anaplasia is seen.
    Vascular invasion --------------------
    Tumour does not invade the renal capsule / invades the renal capsule and is seen in perinephric fat..
    Gerotta’s fascia is -----------------------------------
    Renal sinus involvement is-------------------------------------
    Renal vein involvement is ----------------------------
    Hilar lymph nodes----------------------------------------------------------------------------------
    Foci of nephroblastomatosis are not seen / -----------------type of nephroblastomatosis is present. -------------------------------------------------------------------------------------------------
    Resection margins of ureter, renal vein and renal artery are ---------------------------------Adrenal is --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
    Impression:
    Right / Left radical nephrectomy / Nephrectomy / Partial nephrectomy ,
    Post chemotherapy / History of neo-adjuvent chemotherapy unknown.:
    Wilm’s tumour, ----------------histology, ---------------invading renal capsule / --------------------
    invading Gerotta’s fascia, -- -------involving --------------lymph nodes.



    For further reference log on to: http://clinicalestablishments.gov.in/WriteReadData/2611.pdf

    chemotherapychildren’s cancerDr Anil K D CruzguidelinesLaparoscopic surgerynephrectomyPancreastreatment guidelineswilmsWilms tumorWilms tumour

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    supriya kashyap kashyap
    supriya kashyap kashyap
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