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New Regime for Meningococcal B Vaccine: Guideline


New Regime for Meningococcal B Vaccine: Guideline

Advisory Committee on Immunization Practices,Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report (MMWR), US has recently updated the guideline for Use of MenB-FHbp Serogroup B Meningococcal Vaccine , 2016 .

Following are the major Updated Recommendations :

These recommendations are regarding use of the 2- and 3-dose schedules of MenB-FHbp vaccine (Trumenba) and replace previous ACIP recommendations for use of MenB-FHbp vaccine published in 2015 (3,4). Recommendations regarding use of MenB-4C (Bexsero) are unchanged (3,4).

  • Persons aged ≥10 years at increased risk for serogroup B meningococcal disease (Category A recommendation). For persons at increased risk for meningococcal disease and for use during serogroup B meningococcal disease outbreaks, 3 doses of MenB-FHbp should be administered at 0, 1–2, and 6 months to provide earlier protection and maximize short-term immunogenicity. However, if the second dose of MenB-FHbp is administered at an interval of ≥6 months, a third dose does not need to be administered.
  • Adolescents and young adults aged 16–23 years (Category B recommendation). When given to healthy adolescents who are not at increased risk for meningococcal disease, 2 doses of MenB-FHbp should be administered at 0 and 6 months. If the second dose of MenB-FHbp is administered earlier than 6 months after the first dose, a third dose should be administered at least 4 months after the second dose.
  • Recommendations for use of MenB-4C vaccine are unchanged.
  • The two MenB vaccines are not interchangeable, and the same product must be given for all doses in a series.
  • Either MenB vaccine may be given concomitantly with other vaccines appropriate for this age, but preferably at a different anatomic site.
  • Defer vaccination in women known to be pregnant or lactating unless the woman is at increased risk for serogroup B meningococcal disease, and if her healthcare provider determines that the benefits of vaccination outweigh the potential risks.

Read the full guideline click on the link : https://www.cdc.gov/mmwr/volumes/66/wr/mm6619a6.htm

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Anjali Nimesh

Anjali Nimesh

Anjali Nimesh Joined Medical Dialogue as Reporter in 2016. she covers all the medical specialty news in different medical categories. She also covers the Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in medical filed. She is a graduate from Dr. Bhimrao Ambedkar University. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751
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