Speciality Medical Dialogues
    • facebook
    • twitter
    Login Register
    • facebook
    • twitter
    Login Register
    • Medical Dialogues
    • Education Dialogues
    • Business Dialogues
    • Medical Jobs
    • Medical Matrimony
    • MD Brand Connect
    Speciality Medical Dialogues
    • Editorial
    • News
        • Anesthesiology
        • Cancer
        • Cardiac Sciences
        • Critical Care
        • Dentistry
        • Dermatology
        • Diabetes and Endo
        • Diagnostics
        • ENT
        • Featured Research
        • Gastroenterology
        • Geriatrics
        • Medicine
        • Nephrology
        • Neurosciences
        • Nursing
        • Obs and Gynae
        • Ophthalmology
        • Orthopaedics
        • Paediatrics
        • Parmedics
        • Pharmacy
        • Psychiatry
        • Pulmonology
        • Radiology
        • Surgery
        • Urology
    • Practice Guidelines
        • Anesthesiology Guidelines
        • Cancer Guidelines
        • Cardiac Sciences Guidelines
        • Critical Care Guidelines
        • Dentistry Guidelines
        • Dermatology Guidelines
        • Diabetes and Endo Guidelines
        • Diagnostics Guidelines
        • ENT Guidelines
        • Featured Practice Guidelines
        • Gastroenterology Guidelines
        • Geriatrics Guidelines
        • Medicine Guidelines
        • Nephrology Guidelines
        • Neurosciences Guidelines
        • Obs and Gynae Guidelines
        • Ophthalmology Guidelines
        • Orthopaedics Guidelines
        • Paediatrics Guidelines
        • Psychiatry Guidelines
        • Pulmonology Guidelines
        • Radiology Guidelines
        • Surgery Guidelines
        • Urology Guidelines
    LoginRegister
    Speciality Medical Dialogues
    LoginRegister
    • Home
    • Editorial
    • News
      • Anesthesiology
      • Cancer
      • Cardiac Sciences
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endo
      • Diagnostics
      • ENT
      • Featured Research
      • Gastroenterology
      • Geriatrics
      • Medicine
      • Nephrology
      • Neurosciences
      • Nursing
      • Obs and Gynae
      • Ophthalmology
      • Orthopaedics
      • Paediatrics
      • Parmedics
      • Pharmacy
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
    • Practice Guidelines
      • Anesthesiology Guidelines
      • Cancer Guidelines
      • Cardiac Sciences Guidelines
      • Critical Care Guidelines
      • Dentistry Guidelines
      • Dermatology Guidelines
      • Diabetes and Endo Guidelines
      • Diagnostics Guidelines
      • ENT Guidelines
      • Featured Practice Guidelines
      • Gastroenterology Guidelines
      • Geriatrics Guidelines
      • Medicine Guidelines
      • Nephrology Guidelines
      • Neurosciences Guidelines
      • Obs and Gynae Guidelines
      • Ophthalmology Guidelines
      • Orthopaedics Guidelines
      • Paediatrics Guidelines
      • Psychiatry Guidelines
      • Pulmonology Guidelines
      • Radiology Guidelines
      • Surgery Guidelines
      • Urology Guidelines
    • Home
    • News
    • Cancer
    • Statins may increase...

    Statins may increase survival in colorectal cancer besides lowering LDL C

    Written by Hina Zahid Published On 2020-01-09T19:30:39+05:30  |  Updated On 9 Jan 2020 7:30 PM IST
    Statins may increase survival in colorectal cancer besides lowering LDL C
    About 40 million adults in the U.S. take a statin to lower their cholesterol and reduce the risk of heart disease. Statin use is associated with improved overall survival when used in the preventive setting and in some cancer populations, but data is lacking for colorectal cancer (CRC) patients. Researchers conducted a study to determine the effects of statin therapy on the overall survival of Colorectal cancer patients.

    Some early animal studies had shown that statins could enhance cancer growth in rodents but later studies didn't show higher cancer rates. Rather they have suggested people taking statins are less likely to be diagnosed with prostate cancer and are living longer after a breast, colorectal, kidney or lung cancer diagnosis than people not on statins.


    Dr Chiara Melloni, an associate professor at Duke University School of Medicine in Durham, North Carolina and her colleagues investigated whether statin use affected outcomes in people with colorectal cancer. The findings appearing in Circulation affirm that Statin use at the time of colorectal cancer diagnosis is associated with improved overall survival.


    They used data from the National Veterans Affairs Central Cancer Registry from 2001 to 2011 and defined statin users as patients having 2 or more prescription fill within 6 months relative to CRC diagnosis. The association between statin use (treated as a time-varying covariate) and overall survival was assessed using Cox proportional hazards models in the overall study population and key subgroups.


    They analyzed the medical records of 29,498 veterans who had been diagnosed with colorectal cancer. Of the 29,498 CRC patients identified, 11,340 (38%) were statin users. After about five years of follow-up, those taking a statin at the time of their cancer diagnosis were 31% less likely to die from any cause and 38% less likely to die from colorectal cancer than those not taking the medication, even after adjusting for factors such as the tumour's location and stage.


    "The preliminary findings confirm that statins can have a benefit in overall survival for colorectal cancer patients," said Melloni, who presented the research in November at the American Heart Association's Scientific Sessions conference. Research presented at meetings is considered preliminary until published in a medical journal.


    The latest findings are similar to other studies in breast, prostate and colorectal cancer that show statin users have better outcomes. But striking thing is that statins appear to better protect against colorectal cancer death than they protected against having a heart attack or stroke. Being on a statin lowered the risk of heart attack by 9% and stroke by 23% compared to the nearly 40% reduction in death from colorectal cancer.


    The researchers concluded that Statin use at the time of cancer diagnosis is associated with improved overall survival. The benefit of statin use seems to persist regardless of cancer stage, location, and presence of other cardiovascular comorbidities. Further research is needed to confirm which CRC patients benefit the most from statin therapy.


    For further reference log on to :

    Circulation. 2019;140:A15660
    American Heart AssociationcancercholesterolCirculationColorectal CancerHeart disease
    Source : Circulation

    Disclaimer: This site is primarily intended for healthcare professionals. Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement or prescription. Use of this site is subject to our terms of use, privacy policy, advertisement policy. © 2020 Minerva Medical Treatment Pvt Ltd

    Hina Zahid
    Hina Zahid
      Show Full Article
      Next Story
      Similar Posts
      NO DATA FOUND

      • Email: info@medicaldialogues.in
      • Phone: 011 - 4372 0751

      Website Last Updated On : 12 Oct 2022 7:06 AM GMT
      Company
      • About Us
      • Contact Us
      • Our Team
      • Reach our Editor
      • Feedback
      • Submit Article
      Ads & Legal
      • Advertise
      • Advertise Policy
      • Terms and Conditions
      • Privacy Policy
      • Editorial Policy
      • Comments Policy
      • Disclamier
      Medical Dialogues is health news portal designed to update medical and healthcare professionals but does not limit/block other interested parties from accessing our general health content. The health content on Medical Dialogues and its subdomains is created and/or edited by our expert team, that includes doctors, healthcare researchers and scientific writers, who review all medical information to keep them in line with the latest evidence-based medical information and accepted health guidelines by established medical organisations of the world.

      Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement or prescription.Use of this site is subject to our terms of use, privacy policy, advertisement policy. You can check out disclaimers here. © 2025 Minerva Medical Treatment Pvt Ltd

      © 2025 - Medical Dialogues. All Rights Reserved.
      Powered By: Hocalwire
      X
      We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok