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Portable device THAT detects stroke in 30 seconds, with 92% accuracy


Portable device THAT detects stroke in 30 seconds, with 92% accuracy

In Stroke endovascular therapy within 24 hours is the standard of care for emergent large-vessel occlusion, but the chance of achieving a good outcome decreases by approximately 20 percent for each hour that passes before treatment.That is the reason precisely why the importance of early detection of Stroke is emphasized time and again. A standard physical examination achieves only 40 to 89 percent accuracy in identifying patients with large-vessel occlusion who could benefit from endovascular therapy.Raymond D. Turner at the Medical University of South Carolina (MUSC), Mount Sinai the University of Tennessee Health Sciences Center along with other Clinical investigators have developed a new device worn like a visor can detect the emergent large-vessel occlusion in patients with suspected stroke with 92 percent accuracy.The study has been published in the Journal of Neurointerventional Surgery. 

The volumetric impedance phase shift spectroscopy (VIPS) device (Cerebrotech VisorTM, Cerebrotech Medical Systems, Pleasanton, CA) works by sending low-energy radio waves through the brain that change frequency when passing through fluids. Such waves are reflected back through the brain and then detected by the device. When a patient is having a severe stroke, the brain’s fluids will change, producing an asymmetry in the radio waves detected by the VIPS device. The greater the asymmetry, the more severe the stroke.

The researchers hope that the device will save valuable time — especially important in stroke where time is brain — when it is deployed with emergency medical personnel in the field. This is because the accuracy of the device simplifies the decision made by emergency personnel about where to take patients first, according to Raymond D. Turner, M.D., professor of neurosurgery and chief of the Neuroscience Integrated Center of Clinical Excellence at MUSC. Turner served as principal investigator for MUSC in the VIPS for the Non-Invasive Detection of Hemispheric Bioimpedance Asymmetry in Severe Brain Pathology (VITAL) study reported in the article.

“Transfer between hospitals takes a lot of time,” said Turner. “If we can give the information to emergency personnel out in the field that this is a large-vessel occlusion, that should change their thought process in triage as to which hospital they go to.”

In the study, the VIPS device was deployed with emergency medical personnel in regions served by five Comprehensive Stroke Centers equipped with the endovascular capabilities to treat large-vessel occlusions that underlie severe stroke. Their goal was to use the device to accurately identify severe stroke and then compare the results to established physical examination methods practiced by emergency personnel such as the Prehospital Acute Stroke Severity Scale.

Both healthy participants and patients with suspected stroke were evaluated by emergency personnel using the VIPS device. Three readings were taken and averaged — a process that takes about 30 seconds. Patients were also later evaluated by neurologists who provided definitive diagnoses using neuroimaging.

Compared to the neurologists’ diagnoses, the device displayed 92 percent specificity — the ability to detect the difference between patients with severe stroke and those with other conditions such as mild stroke or healthy participants with no brain pathology. This places the VIPS device above standard physical examination tools used by emergency personnel that display specificity scores between 40 and 89 percent.

The VIPS device is made by Cerebrotech Medical Systems, which paid consultants to analyze the neuroimaging data independently. The neuroimaging data was needed to teach the VIPS device which radio waves were indicative of stroke. Yet the consultants did not have access to the VIPS radio wave data during their review of the images, thereby eliminating the potential of the consultants to choose data that might artificially inflate the device’s accuracy. It is also not clear how the device would work for patients with cranial implants, as metal interferes with the device’s operating radio frequencies.

The device’s success may be found in its ability to give emergency personnel a clear answer as to whether a patient is experiencing a severe stroke. The VIPS device requires very little training to operate compared to that required to learn standard emergency examination skills, thereby reducing the possibility of human error during emergency diagnosis.

In their next steps, the researchers are undertaking the VITAL 2.0 study to determine if the VIPS device can use complex machine learning algorithms to teach itself how to discriminate between minor and severe stroke without the help of neurologists. If so, the VIPS device could have widespread clinical implications, helping emergency personnel decide whether to take a patient to a comprehensive stroke center or a primary stroke center for treatment.

Turner likens the use of the VIPS device in detecting severe stroke to the use of electrocardiography (ECG) to definitively detect acute myocardial infarction. He predicts that the device has the potential to be used widely by emergency personnel but also to appear in other public spaces. “This could potentially be something like a defibrillator,” said Turner. “You can find out if a patient is having a stroke, just like you can put a defibrillator on a patient to see if they’re having a heart attack.”

This study was funded by Cerebrotech Medical Systems.

For more details click on the link: http://dx.doi.org/10.1136/neurintsurg-2017-013690

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Anjali Nimesh

Anjali Nimesh

Anjali Nimesh Joined Medical Dialogue as Reporter in 2016. she covers all the medical specialty news in different medical categories. She also covers the Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in medical filed. She is a graduate from Dr. Bhimrao Ambedkar University. She can be contacted at editorial@medicaldialogues.in Contact no. 011-43720751
Source: Eureka Alert

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