Diabetic retinopathy (DR) is among the most common diabetic complications and is the leading cause of blindness among working-aged individuals worldwide.Previous studies have shown an inverse association between Vitamin D Deficiency and Diabetic Retinopathy in various populations but this association has not been studied in Indian population. Dr. Ashinne B at Duke University School of Medicine, Durham, North Carolina and associates have conducted a retrospective study and found that Low level of serum 25-hydroxyvitamin D (25(OH)D) is associated with increased severity of diabetic retinopathy (DR) in Asian Indians with type 2 diabetes mellitus (T2DM). The study also found that vitamin D deficiency (VDD) is associated with a 2-fold increased risk for proliferative DR (PDR).The new study has been published in the journal Diabetes Research and Clinical Practice.
Researchers in this retrospective study analyzed medical records of 3054 patients with T2DM (age, >18 years) who underwent detailed retinal examination with DR severity grading. DR grades were classified as no DR, mild nonproliferative DR (NPDR), moderate NPDR, severe NPDR, or PDR. They compared serum (25(OH)D) levels between patients with DR and those without DR.