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Insomnia associated with increased risk of heart attack and stroke: European Journal of Preventive Cardiology.


Insomnia associated with increased risk of heart attack and stroke: European Journal of Preventive Cardiology.

Sophia Antipolis : Insomnia is associated with increased risk of heart attack and stroke, according to research published today in the European Journal of Preventive Cardiology.

“Sleep is important for biological recovery and takes around a third of our lifetime, but in modern society more and more people complain of insomnia,” said first author Qiao He, a Master’s degree student at China Medical University, Shenyang, China. “For example, it is reported that approximately one-third of the general population in Germany has suffered from insomnia symptoms.”

“Researchers have found associations between insomnia and poor health outcomes,” continued Miss He. “But the links between insomnia and heart disease or stroke have been inconsistent.”

The current meta-analysis assessed the association between insomnia symptoms and incidence or death from cardiovascular disease (acute myocardial infarction, coronary heart disease, heart failure), stroke, or a combination of events. Insomnia symptoms included difficulty initiating sleep, difficulty maintaining sleep, early-morning awakening, and non-restorative sleep.

The authors analysed 15 prospective cohort studies with a total of 160 867 participants. During a median follow-up of three to 29.6 years, there were 11 702 adverse events.

There were significant associations between difficulty initiating sleep, difficulty maintaining sleep, and non-restorative sleep and the risk of heart disease and stroke, with increased relative risks of 1.27, 1.11, and 1.18, respectively, compared to those not experiencing these insomnia symptoms. There was no association between early-morning awakening and adverse events.

Miss He said: “We found that difficulty initiating sleep, difficulty maintaining sleep, or non-restorative sleep were associated with 27%, 11%, and 18% higher risks of cardiovascular and stroke events, respectively.”

“The underlying mechanisms for these links are not completely understood,” continued Miss He. “Previous studies have shown that insomnia may change metabolism and endocrine function, increase sympathetic activation, raise blood pressure, and elevate levels of pro inflammatory and inflammatory cytokines all of which are risk factors for cardiovascular disease and stroke.”

Women with insomnia symptoms had a slightly higher risk of cardiovascular and stroke events than men, especially for non-restorative sleep, but the difference between sexes did not reach statistical significance.

Miss He said: “We cannot conclude that insomnia is more dangerous for women, given the limitations of meta-analyses and the lack of a statistically significant difference between sexes. However, we do know that women are more prone to insomnia because of differences in genetics, sex hormones, stress, and reaction to stress. It may therefore be prudent to pay more attention to women’s sleep health.”

Miss He concluded: “Sleep disorders are common in the general population and sleep health should be included in clinical risk assessment. Health education is needed to increase public awareness of insomnia symptoms and the potential risks, so that people with sleep problems are encouraged to seek help.”

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supriya kashyap

supriya kashyap

Supriya Kashyap Joined Medical Dialogue as Reporter in 2015 . she covers all the medical specialty news in different medical categories. She also covers the Medical guidelines, Medical Journals, rare medical surgeries as well as all the updates in medical filed. She is a graduate from Delhi University. She can be contacted at supriya.kashyap@medicaldialogues.in Contact no. 011-43720751
Source: EurekAlert

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  1. If persons with strict titration of drugs for hypertension or any other cardiovascular problems like atrial fibrillation or any of its cause are under strict control or treatment then (stroke or any cardiac failure ) such events should not be occurring . These events should be taking place in patients who are uncontrolled and without medication for cardiology presenting as complications . Insomnia secondary to causes of GIT origin should not be leading to cerebral stroke or dilated hearts . Such studies need further and deeper evaluations .