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India Antibiotic Guideline for Skin and Soft Tissue Infections

India Antibiotic Guideline for Skin and Soft Tissue Infections

In 2016 National Centre For Disease, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.

Following are major recommendation for  Skin & Soft Tissue Infections:

Condition Likely Causative Organisms Empiric antibiotics (presumptive antibiotics) Alternative antibiotics Comments
Cellulitis Streptococcus pyogenes(common), S.aureus AmoxicillinClavulanate 1.2gm IV TDS/625 mg oral TDS


Ceftriaxone 2gm IV OD

Clindamycin 600-900mg IV TDS Treat for 5-7 days.
Furunculosis S.aureus AmoxicillinClavulanate 1.2gm IV/Oral 625 TDS


Ceftriaxone 2gm IV OD Duration – 5-7 days

Clindamycin 600-900mg IV TDS Get pus cultures before starting antibiotics
Necrotizing fasciitis Streptococcus pyogenes, S. aureus, anaerobes, Enterobacteriaceae (polymicrobial) PiperacillinTazobactam 4.5gm IV 6hourly

or CefoperazoneSulbactam 3gm IV 12hourly


Clindamycin 600-900mg IV 8 hourly Duration depends on the progress

Imipenem 1g IV8hourly


Meropenem 1gm IV 8hourly


Clindamycin 600-900mg IV TDS/linezolid 600 mg IV BD/daptomycin 6mg/kg/day

Early surgical intervention crucial

You can read the full Guideline by clicking on the following link :

Source: self

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  1. user
    Kenit P. Ardeshna February 4, 2017, 2:21 pm

    Link is not working