India Antibiotic Guideline for Skin and Soft Tissue Infections
In 2016 National Centre For Disease, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.
Following are major recommendation for Skin & Soft Tissue Infections:
| Condition | Likely Causative Organisms | Empiric antibiotics (presumptive antibiotics) | Alternative antibiotics | Comments |
| Cellulitis | Streptococcus pyogenes(common), S.aureus | AmoxicillinClavulanate 1.2gm IV TDS/625 mg oral TDS or Ceftriaxone 2gm IV OD | Clindamycin 600-900mg IV TDS | Treat for 5-7 days. |
| Furunculosis | S.aureus | AmoxicillinClavulanate 1.2gm IV/Oral 625 TDS or Ceftriaxone 2gm IV OD Duration – 5-7 days | Clindamycin 600-900mg IV TDS | Get pus cultures before starting antibiotics |
| Necrotizing fasciitis | Streptococcus pyogenes, S. aureus, anaerobes, Enterobacteriaceae (polymicrobial) | PiperacillinTazobactam 4.5gm IV 6hourly or CefoperazoneSulbactam 3gm IV 12hourly AND Clindamycin 600-900mg IV 8 hourly Duration depends on the progress | Imipenem 1g IV8hourly or Meropenem 1gm IV 8hourly AND Clindamycin 600-900mg IV TDS/linezolid 600 mg IV BD/daptomycin 6mg/kg/day | Early surgical intervention crucial |
You can read the full Guideline by clicking on the following link :
http://www.ncdc.gov.in/writereaddata/linkimages/AMR_guideline7001495889.pdf
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