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India Antibiotic Guideline For Infections In Burn and Plastic Surgery

India Antibiotic Guideline For Infections In Burn and Plastic Surgery

In 2016 National Centre For Disease, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.

Following are major recommendation

Infections In Burns Patient : 

Condition Likely Causative Organism Empiric antibiotics Alternative antibiotics Comments
For burns wound that is clinically or microbiologically not infected Prophylactic parenteral antibiotics in burns are NOT indicated

Topical antibiotics to be given after debridement

For burns wound that are clinically or microbiologically infected Strep pyogenes, Enterobacter sp., S. aureus,

S. epidermidis, Pseudomonas, fungi (rare)

i. Burn wound sepsis Pipercillin-tazobactam


Cefoperazone-sulbactam or With or without:

  •  Vancomycin //Teicoplanin (if there is suspicion for MRSA)
  •  Antifunal Therapy – When extensive burns and patient not responding to antibiotics            o If hemodynamically stable: fluconazole          o If hemodynamically unstable: Echinocandin

Burn wound cellulitis


or                Clindamycin

or                 Vancomycin if there is suspicion for MRSA

With and without (for burns involving the lower extremity or feet or                             burns in patients with diabetes)




Carbapenem +/- Vancomycin/ Teicoplanin Antibiotic choices are dependent on the antibiogram of the individual institution. Surgical debridement as necessary. Amphotericin B is toxic to all burn patient as renal system compromised, hence Caspofungin may be used.

Prophylaxis in Plastic Surgery Surgical

prophylaxsis: Inj Cefuroxime 1.5 g/ Cefazolin IV just before incision single dose.


You can read the full Guideline by clicking on the following link :

Source: self

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