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    • India Antibiotic...

    India Antibiotic Guideline for Cardiovascular Infections

    Written by supriya kashyap kashyap Published On 2016-08-28T16:21:42+05:30  |  Updated On 28 Aug 2016 4:21 PM IST
    India Antibiotic Guideline for Cardiovascular Infections

    In 2016 National Centre For Disease Control, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.



    Following are major recommendation


    Cardiovascular Infections:


































    ConditionLikely causative OrganismEmpiric antibiotics (presumptive antibiotics)Alternative antibioticsComments
    Infective Endocarditis:

    Native valve (awaiting cultures) Indolent
    Viridans Streptococci, other Streptococci, EnterococciPenicillin G 20MU IV divided doses, 4 hourly

    or

    Ampicillin 2gm iv 4h AND

    Gentamicin 1mg/kg im or iv 8h

    Duration: 4-6 weeks
    Vancomycin 15mg/kg IV 12 hourly (maximum 1g 12 hourly)//teicplani n 12mg/kg IV 12 hourly x 3 doses followed by 6 - 12 mg once daily IV depending upon severity + Gentamicin 1mg/kg IM or IV

    8 hourly Duration: 4-6 weeks

    or

    Daptomycin 6mg/kg IV once a day Duration: 4-6 weeks
    If patient is stable, ideally waitblood cultures.

    Antibiotic choice as per sensitivity results.

    Guidance from Infectious disease specialist or clinical microbiologist is recommended
    Infective Endocarditis:

    Native valve (awaiting cultures) In Severe Sepsis
    S.aureus

    (MSSA or MRSA) Risk for gramnegative bacilli
    Vancomycin 25- 30 mg/kg loading followed by 15-20 mg/kg IV 12 hourly (maximum 1gm

    12

    hourly)/teicoplan in 12mg/kg IV 12 hourly x 3 doses followed

    by 6 -12 mg once daily IV depending upon severity

    AND

    Meropenem 1gm IV 8h Duration: 4-6 weeks
    Daptomycin 6mg/kg IV once a day

    AND

    Meropenem 1gm IV q8h

    Duration: 4-6 weeks
    Modify antibiotics based on culture results and complete 4-6 weeks of antibiotics
    Infective Endocarditis: Prosthetic Valve awaiting CulturesVancomycin 15mg/kg IV 12 hourly (maximum 1gm

    12

    hourly)/teicoplan in 12mg/kg IV 12 hourly x 3 doses followed by 6 -12 mg once daily IV

    depending upon severity +

    Gentamicin 1mg/kg q12h IV
    Daptomycin can be used in place of Vancomycin/ Teicoplanin for patients unresponsive to or intolerant of Vancomycin/Tei coplanin or with Vancomycin/Gly copeptideresistant isolatesAntibiotic choice as per sensitivity. Guidance from Infectious disease specialist or microbiologist is recommended.

    You can read the full Guideline by clicking on the following link :


    http://www.ncdc.gov.in/writereaddata/linkimages/AMR_guideline7001495889.pdf

    Cardiovascular InfectionsDirectorate General of health servicesGovernment of IndiaInfectious diseasesMinistry of Health & Family WelfareNational Centre For Disease

    Disclaimer: This site is primarily intended for healthcare professionals. Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement or prescription. Use of this site is subject to our terms of use, privacy policy, advertisement policy. © 2020 Minerva Medical Treatment Pvt Ltd

    supriya kashyap kashyap
    supriya kashyap kashyap
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