IBD patients are at higher risk of heart attack and mortality
South Korea: Crohn’s disease (CD) patients are at a higher risk for heart attack or myocardial infarction (MI) and this risk is starker in female patients and those aged <40 years.
The researchers used claim codes for identification of the patients diagnosed with IBD between 2006 and 2009 (10,708 with CD; 26,769 with UC) and they were matched with people who did not have IBD. They calculated risk for the three primary outcomes of myocardial infarction, stroke and death.
Key findings include:
- Patients with CD had a higher risk for myocardial infarction than controls (incidence ratio = 1.64 per 1,000 person-years).
- The risk was more prominent among patients older than 40 years (IR = 0.69 per 1,000 person-years) and among women (IR = 2.35 per 1,000 person-years).
- Women with UC, but not men, were at higher risk for myocardial infarction (IR = 2.01 per 1,000 person-years).
"Patients with CD are at a higher risk of heart attack and mortality than in the general population. The higher risk of MI in female IBD patients and disease-specific mortality among IBD should be further studied in the future," concluded the authors.
To read the complete study log on to https://doi.org/10.1111/apt.15446