Dr. Charlotte Wessel Skovlund and associates conducted a nationwide prospective cohort study in Denmark to assess the relative risk of suicide attempt and suicide in users of hormonal contraception and found that Use of hormonal contraception was positively associated with subsequent suicide attempt and suicide. The study was published in American Journal of Psychiatry.
In the study, the authors assessed associations between hormonal contraceptive use and suicide attempt and suicide in all women in Denmark who had no psychiatric diagnoses, antidepressant use, or hormonal contraceptive use before age 15 and who turned 15 during the study period, which extended from 1996 through 2013. Nationwide registers provided individually updated information about use of hormonal contraception, suicide attempt, suicide, and potential confounding variables. Psychiatric diagnoses or antidepressant use during the study period were considered potential mediators between hormonal contraceptive use and risk of suicide attempt. Adjusted hazard ratios for suicide attempt and suicide were estimated for users of hormonal contraception as compared with those who never used hormonal contraception.
For more details click on the link: https://doi.org/10.1176/appi.ajp.2017.17060616