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    • Gouty Arthritis -...

    Gouty Arthritis - Standard Treatment Guidelines

    Written by supriya kashyap kashyap Published On 2017-04-15T09:54:53+05:30  |  Updated On 15 April 2017 9:54 AM IST
    Gouty Arthritis - Standard Treatment Guidelines

    Gout characterized by recurrent attacks of acute inflammatory arthritis— a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.


    Ministry of Health and Family Welfare, Government of India has issued the Standard Treatment Guidelines for Gouty Arthritis. Following are the major recommendations :



    Case definition:


    Affluent males are the usual victims. It very rarely affects premenopausal women & such a patient should be viewed with suspicion if a diagnosis of gout is made.


    Gout can present in a number of ways, although the most usual is a recurrent attack of acute inflammatory arthritis. The metatarsalphalangeal joint at the base of the big toe is affected most often, accounting for half of cases. Other joints, such as the heels, knees, wrists and fingers, may also be affected. Joint pain usually begins over 2– 4 hours and during the night. Other symptoms that may occur along with the joint pain include fatigue and a high fever.


    Long-standing elevated uric acid levels (hyperuricemia) may result in other symptomatology, including hard, painless deposits of uric acid crystals known as tophi. Extensive tophi may lead to chronic arthritis due to bone erosion. Elevated levels of uric acid may also lead to crystals precipitating in the kidneys, resulting in stone formation and subsequent urate nephropathy.



    Incidence of The Condition In Our Country


    Gout affects around 1–2% of the Western population at some point in their lifetimes, and is becoming more common. A number of factors have been found to influence rates of gout, including age, race, and the season of the year. In men over the age of 30 and women over the age of 50, prevalence is 2%



    Differential Diagnosis


    Differential diagnosis of Gout include


    1. Septic Arthritis


    2. Pseudo Gout


    3. Rheumatoid Arthritis



    Prevention And Counseling


    Both Dietary and lifestyle changes can decrease uric acid levels.


    i. reducing intake of food such as meat and seafood,


    ii. consuming adequate vitamin C,


    iii. limiting alcohol and fructose consumption


    iv. avoiding obesity.


    v. Coffee, but not tea, consumption is associated with a lower risk of gout.



    Optimal Diagnostic Criteria, Investigations, Treatment & Referral Criteria


    SITUATION 1: At Secondary Hospital / Non Metro situation : Optimal standards of Treatment in situations where technology and resources are limited



    Clinical Diagnosis :


    Usual presentation is acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.



    Investigations:


    1. X Ray


    2. Serum Uric Acid Level (Suggestive; to be confirmed by 3 below)


    3. MSU crystals in Synovial fluid and tophi (Essential for diagnosis)


    4. Complete Blood Picture


    5. ESR


    6. CRP


    7. Renal function test



    Treatment:


    not applicable



    Standard Operating procedure


    In Patient


    1. Surgery




    • Excision of symptomatic tophi


    Out Patient


    1.Acute Attack




    • NSIADS

    • Colchicine

    • Steroids


    2. Chronic (No role in acute attack)




    • Allopurinol

    • Febuxostat

    • Probenacid


    3. Physical Therapy


    Day Care


    1. Injectable medications


    2. Intra articular Steroid Injection



    Referral criteria:


    For further evaluation and management of cases not responding to conventional therapy.


    SITUATION 2: At Super Specialty facility in Metro Location where higher end technology is available



    Clinical Diagnosis :


    Usual presentation is acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues.



    Investigations:


    1. X Ray


    2. Serum Uric Acid Level (Suggestive; to be confirmed by 3 below)


    3. MSU crystals in Synovial fluid and tophi (Essential for diagnosis)


    4. Complete Blood Picture


    5. ESR


    6. CRP


    7. Renal function test



    Treatment:


    not applicable



    Standard Operating procedure


    In Patient


    1. Surgery




    • Excision of symptomatic tophi


    Out Patient


    1.Acute Attack




    • NSIADS

    • Colchicine

    • Steroids


    2. Chronic (No role in acute attack)




    • Allopurinol

    • Febuxostat

    • Probenacid


    3. Physical Therapy


    Day Care


    1. Injectable medications


    2. Intra articular Steroid Injection



    Referral criteria:


    not applicable



    WHO DOES WHAT? And TIMELINES


    Doctor


    Early diagnosis and appropriate treatment. Counsel the patient for prevention and dietary advice.


    Nurse


    counseling the patient. Injectable treatment


    Technician


    Appropriate bracing


    Physiotherapy



    Resources Required For One Patient / Procedure (Patient Weight 60 Kgs)


    (Units to be specified for human resources, investigations, drugs and consumables and equipment. Quantity to also be specified)



























    SituationHuman Resources InvestigationsDrugs & Consumables Equipment
    1.Doctor

    Nurse

    Technician
    1. X Ray

    2. MSU crystals in Synovial fluid and tophi

    3. Serum Uric Acid Level

    4. Complete Blood Picture

    5. ESR

    6. CRP

    7. Renal function test
    e. NSAIDs

    f. Colchicine

    g. Steroid

    h. Uric acid lowering agents

    i. Consumables for surgery
    Lab

    equipment

    Imaging equipment

    Exercise equipments

    Equipments

    for

    Operating Room
    2.

    (In Addition to Situation 1)
    GoutGovernment of IndiaMinistry of Health and Family Welfarerheumatoid arthritisStandard Treatment Guidelines

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    supriya kashyap kashyap
    supriya kashyap kashyap
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