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GOI Guidelines For Surgical Antimicrobial Prophylaxis


GOI Guidelines For Surgical Antimicrobial Prophylaxis

In 2016 National Centre For Disease Control, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.

Following are major recommendation for 

Surgical Antimicrobial Prophylaxis : 

  • To be administered within 1 hr before the surgical incision.
  • Single dose is recommended. Consider for second intra-operative dose in prolong surgery based on the choice of antibiotic used for prophylaxis.
  •  Prophylaxis should not be given beyond surgery duration (except for cardiothoracic surgery, up to 48 hours permissible)
  •  Choice of the prophylaxis should be based on the local antibiogram.
SURGERY MEDICATION
Breast Inj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Gastroduodenal & biliary Inj.Cefaperazone- Sulbactam 2gm IV stat & BD for 24hrs(maximum)
ERCP Inj.Piperacillin-Tazobactum 4.5gm or Inj.Cefaperazone- Sulbactam 2gm IV stat
Cardiothoracic Inj.Cefuroxime 1.5gm IV stat & BD for 48hrs
Colonic surgery Inj.Cefaperazone- Sulbactam 2gm IV stat & BD for 24hrs(maximum)
Abdominal surgery (hernia) Inj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Head & Neck/ ENT Inj.Cefazolin 2gm IV stat
Neurosurgery Inj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Obstetrics& Gynecology Inj.Cefuroxime 1.5gm IV stat
Orthopaedic Inj.Cefuroxime 1.5gm IV stat & BD for 24 hrs(maximum)

or

Inj.Cefazolin 2gm IV stat

Open reduction of closed fracture with internal fixation- Inj.Cefuroxime 1.5gm IV stat and q 12h or Inj.Cefazolin 2gm IV stat and q 12h for 24 hrs

Trauma Inj.Cefuroxime 1.5gm IV stat and q 12h (for 24 hrs) or Inj.Ceftriaxone 2gm IV OD
Urologic procedures Antibiotics only to patients with documented bacteriuria
Trans- rectal prostatic surgery Inj.Cefaperazone- Sulbactam 2gm IV stat

You can read the full Guideline by clicking on the following link :

http://www.ncdc.gov.in/writereaddata/linkimages/AMR_guideline7001495889.pdf


Source: self

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