Speciality Medical Dialogues
    • facebook
    • twitter
    Login Register
    • facebook
    • twitter
    Login Register
    • Medical Dialogues
    • Education Dialogues
    • Business Dialogues
    • Medical Jobs
    • Medical Matrimony
    • MD Brand Connect
    Speciality Medical Dialogues
    • Editorial
    • News
        • Anesthesiology
        • Cancer
        • Cardiac Sciences
        • Critical Care
        • Dentistry
        • Dermatology
        • Diabetes and Endo
        • Diagnostics
        • ENT
        • Featured Research
        • Gastroenterology
        • Geriatrics
        • Medicine
        • Nephrology
        • Neurosciences
        • Nursing
        • Obs and Gynae
        • Ophthalmology
        • Orthopaedics
        • Paediatrics
        • Parmedics
        • Pharmacy
        • Psychiatry
        • Pulmonology
        • Radiology
        • Surgery
        • Urology
    • Practice Guidelines
        • Anesthesiology Guidelines
        • Cancer Guidelines
        • Cardiac Sciences Guidelines
        • Critical Care Guidelines
        • Dentistry Guidelines
        • Dermatology Guidelines
        • Diabetes and Endo Guidelines
        • Diagnostics Guidelines
        • ENT Guidelines
        • Featured Practice Guidelines
        • Gastroenterology Guidelines
        • Geriatrics Guidelines
        • Medicine Guidelines
        • Nephrology Guidelines
        • Neurosciences Guidelines
        • Obs and Gynae Guidelines
        • Ophthalmology Guidelines
        • Orthopaedics Guidelines
        • Paediatrics Guidelines
        • Psychiatry Guidelines
        • Pulmonology Guidelines
        • Radiology Guidelines
        • Surgery Guidelines
        • Urology Guidelines
    LoginRegister
    Speciality Medical Dialogues
    LoginRegister
    • Home
    • Editorial
    • News
      • Anesthesiology
      • Cancer
      • Cardiac Sciences
      • Critical Care
      • Dentistry
      • Dermatology
      • Diabetes and Endo
      • Diagnostics
      • ENT
      • Featured Research
      • Gastroenterology
      • Geriatrics
      • Medicine
      • Nephrology
      • Neurosciences
      • Nursing
      • Obs and Gynae
      • Ophthalmology
      • Orthopaedics
      • Paediatrics
      • Parmedics
      • Pharmacy
      • Psychiatry
      • Pulmonology
      • Radiology
      • Surgery
      • Urology
    • Practice Guidelines
      • Anesthesiology Guidelines
      • Cancer Guidelines
      • Cardiac Sciences Guidelines
      • Critical Care Guidelines
      • Dentistry Guidelines
      • Dermatology Guidelines
      • Diabetes and Endo Guidelines
      • Diagnostics Guidelines
      • ENT Guidelines
      • Featured Practice Guidelines
      • Gastroenterology Guidelines
      • Geriatrics Guidelines
      • Medicine Guidelines
      • Nephrology Guidelines
      • Neurosciences Guidelines
      • Obs and Gynae Guidelines
      • Ophthalmology Guidelines
      • Orthopaedics Guidelines
      • Paediatrics Guidelines
      • Psychiatry Guidelines
      • Pulmonology Guidelines
      • Radiology Guidelines
      • Surgery Guidelines
      • Urology Guidelines
    • Home
    • News
    • Cardiac Sciences
    • Daily Dose Aspirin...

    Daily Dose Aspirin dangerous for 75 year old Plus, Warns Lancet Study

    Written by Anjali Nimesh Nimesh Published On 2017-06-14T17:45:29+05:30  |  Updated On 14 Jun 2017 5:45 PM IST
    Daily Dose Aspirin dangerous for 75 year old Plus, Warns Lancet Study

    PARIS: Long-term, daily use of aspirin to prevent blood clots in very elderly patients leads to an increased risk of serious or fatal internal bleeding, researchers said on Wednesday.


    Heartburn medication would allows people 75 years and older to keep the preventative benefits of aspirin while avoiding its dangerous side-effects, they reported in the medical journal The Lancet.


    Even among people with no history of heart problems or stroke, the risk of gastrointestinal bleeding goes up with age for aspirin users, other research has shown.


    Roughly half of all adults 75 and over in the US and Europe take small daily doses of aspirin - ranging from 75 to 150 milligrams - or other clot-inhibiting drugs.


    A normal dose for a headache is 325 to 600 mg.


    Lifelong treatment with such medications is especially recommended for patients who have suffered a heart attack or stroke.


    But the clinical tests underlying these recommendations involved mostly patients younger than 75 who had taken aspirin for only a couple years.


    As a result, how much the risk of bleeding might rise with age was largely unknown.


    To find out more, Peter Rothwell from the University of Oxford led a team of researchers in examining medical records for more than 3,000 patients who had had a stroke or heart attack, and taken daily aspirin or its equivalent for many years.


    Half the patients were 75 or older at the start of the period covered by the study.


    Over the following decade, 314 patients were admitted to hospital for bleeding.


    The risk of that happening increased sharply with age: for patients under 65, the annual rate of hospital admissions due to bleeding was 1.5 percent; for patients 75 to 84, the rate rose to 3.5 percent; and for those over 85 it was five percent.


    The chances that bleeding was disabling or fatal, while lower, increased in roughly the same proportions across the different age groups.


    "We have known for some time that aspirin increases the risk of bleeding in elderly patients," Rothwell said in a statement. "But our study gives us a much clearer understanding of the size of the increased risk and the severity of the consequences."


    The researchers suggest that taking proton pump inhibitors (PPI) - a kind of heartburn medication - could reduce bleeding in the upper gastrointestinal tract by up to 90 percent.


    "There is some evidence that long-term PPI use might have some small risks," Rothwell noted.


    But "the new data should provide reassurance that the benefits of PPI use at older age outweigh the risks."


    Treatment programmes should be reviewed every three to five years in very elderly patients who take aspirin and PPIs together, the authors said.


    Several experts not involved in the study praised its methodology and endorsed its conclusions.


    "It is clear from the data presented that - in the over-75s - taking PPI along with aspirin was associated with a reduced likelihood of bleeding," said Tony Fox, a professor in the Pharmaceutical Medicine Group at King's College London.

    Bleedingbleeding riskblood clotsgastrointestinal bleedingheart problemsheart-attackjournal The Lancetmajor bleedPeter RothwellPPIProton pump inhibitorsstrokeThe Lancet
    Source : AFP

    Disclaimer: This site is primarily intended for healthcare professionals. Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement or prescription. Use of this site is subject to our terms of use, privacy policy, advertisement policy. © 2020 Minerva Medical Treatment Pvt Ltd

    Anjali Nimesh Nimesh
    Anjali Nimesh Nimesh
      Show Full Article
      Next Story
      Similar Posts
      NO DATA FOUND

      • Email: info@medicaldialogues.in
      • Phone: 011 - 4372 0751

      Website Last Updated On : 12 Oct 2022 7:06 AM GMT
      Company
      • About Us
      • Contact Us
      • Our Team
      • Reach our Editor
      • Feedback
      • Submit Article
      Ads & Legal
      • Advertise
      • Advertise Policy
      • Terms and Conditions
      • Privacy Policy
      • Editorial Policy
      • Comments Policy
      • Disclamier
      Medical Dialogues is health news portal designed to update medical and healthcare professionals but does not limit/block other interested parties from accessing our general health content. The health content on Medical Dialogues and its subdomains is created and/or edited by our expert team, that includes doctors, healthcare researchers and scientific writers, who review all medical information to keep them in line with the latest evidence-based medical information and accepted health guidelines by established medical organisations of the world.

      Any content/information on this website does not replace the advice of medical and/or health professionals and should not be construed as medical/diagnostic advice/endorsement or prescription.Use of this site is subject to our terms of use, privacy policy, advertisement policy. You can check out disclaimers here. © 2025 Minerva Medical Treatment Pvt Ltd

      © 2025 - Medical Dialogues. All Rights Reserved.
      Powered By: Hocalwire
      X
      We use cookies for analytics, advertising and to improve our site. You agree to our use of cookies by continuing to use our site. To know more, see our Cookie Policy and Cookie Settings.Ok