Vitamin D supplementation - a potential treatment for non‐motor Parkinson's disease, finds study
By - Dr. Kamal Kant Kohli Kohli
Published On 2019-08-07 13:45 GMT | Update On 2021-08-19 11:14 GMT
Vitamin D may help treat non-motor symptoms of Parkinson's disease, finds a new study. Therefore Vitamin D supplementation may be a potential treatment for non‐motor Parkinson's disease. The study has been published in the journal Acta Neurologica Scandinavia.
Vitamin D deficiency is widespread in patients with Parkinson's disease (PD). The researchers aimed to determine whether serum vitamin D levels correlated with bone mineral density (BMD) and non‐motor symptoms in patients with Parkinson's disease.
The role of vitamin D in bone health has been known for over a century. More recent research has suggested that vitamin D may play a role in the muscular, immune, endocrine, and central nervous systems.
Previous cross-sectional studies have shown that Parkinson's disease (PD) patients have lower serum 25-hydroxy vitamin D (25(OH)D) concentrations than controls. Vitamin D deficiency was associated with increased disease severity and cognitive impairment in prevalent Parkinson's disease patients.
"As various non-motor symptoms place a burden on individuals with Parkinson's disease and their caregivers, vitamin D might be a potential add-on therapy for improving these neglected symptoms," said senior author Chun Feng Liu, MD, PhD, of the Second Affiliated Hospital of Soochow University, in China.
In the study of 182 patients with Parkinson's disease and 185 healthy controls, patients with Parkinson's disease had significantly lower levels of vitamin D in their blood. Also, patients with lower vitamin D levels were more likely to fall, and to experience sleep problems, depression, and anxiety.
"As various non-motor symptoms place a burden on individuals with Parkinson's disease and their caregivers, vitamin D might be a potential add-on therapy for improving these neglected symptoms," said senior author Chun Feng Liu, MD, PhD, of the Second Affiliated Hospital of Soochow University, in China.
The researchers concluded that in patients with PD, vitamin D levels significantly correlated with falls and some non‐motor symptoms. However, no associations were found between BMD and the serum 25(OH)D levels in patients with Parkinson's disease. Thus, vitamin D supplementation is a potential therapeutic for non‐motor Parkinson's disease.
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