Long-term safety and efficacy of dupilumab in atopic dermatitis confirmed in two studies

Published On 2019-10-10 13:45 GMT   |   Update On 2021-08-11 11:23 GMT

Results of two studies have demonstrated the long term safety and efficacy of dupilumab in atopic dermatitis. The results of these latest studies have been reported in the British Journal of Dermatology.


The results from these latest studies, which are reported in the British Journal of Dermatology, in an open-label trial and a subsequent phase III open-label extension trial reinforce findings from an earlier short-term trial that adolescents with moderate-to-severe atopic dermatitis, or eczema, can experience significant improvements with dupilumab.


Dupilumab works by stopping the action of certain substances in the body that cause the symptoms of eczema. Specifically, it is a monoclonal antibody against the interleukin-4 receptor alpha.


"Adolescents with moderate-to-severe atopic dermatitis have a high disease burden that negatively affects the quality of life, and patients are in need of therapies that can be used long-term," said senior author Ashish Bansal, MD, of Regeneron Pharmaceuticals, Inc., in Tarrytown, New York. "Results from these trials show that dupilumab provides substantial and sustained clinical benefit to these patients with an acceptable safety profile."


For more details click on the link: http://dx.doi.org/10.1111/bjd.18476

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