India Antibiotic Guideline For Infections In Burn and Plastic Surgery

Published On 2017-12-09 13:31 GMT   |   Update On 2017-12-09 13:31 GMT

In 2016 National Centre For Disease, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.



Following are major recommendation


Infections In Burns Patient :
























Condition Likely Causative Organism Empiric antibiotics Alternative antibiotics Comments
For burns wound that is clinically or microbiologically not infectedProphylactic parenteral antibiotics in burns are NOT indicated

Topical antibiotics to be given after debridement
For burns wound that are clinically or microbiologically infectedStrep pyogenes, Enterobacter sp., S. aureus,

S. epidermidis, Pseudomonas, fungi (rare)
i. Burn wound sepsis Pipercillin-tazobactam

or

Cefoperazone-sulbactam or With or without:

  • Vancomycin //Teicoplanin (if there is suspicion for MRSA)

  • Antifunal Therapy – When extensive burns and patient not responding to antibiotics o If hemodynamically stable: fluconazole o If hemodynamically unstable: Echinocandin


Burn wound cellulitis

Cefazolin

or Clindamycin

or Vancomycin if there is suspicion for MRSA

With and without (for burns involving the lower extremity or feet or burns in patients with diabetes)

Pipercillin-tazobactam

or

cefoperazone-sulbactam
Carbapenem +/- Vancomycin/ TeicoplaninAntibiotic choices are dependent on the antibiogram of the individual institution. Surgical debridement as necessary. Amphotericin B is toxic to all burn patient as renal system compromised, hence Caspofungin may be used.

Prophylaxis in Plastic Surgery Surgical

prophylaxsis: Inj Cefuroxime 1.5 g/ Cefazolin IV just before incision single dose.

 

You can read the full Guideline by clicking on the following link :

http://www.ncdc.gov.in/writereaddata/linkimages/AMR_guideline7001495889.pdf

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