GOI Guidelines For Surgical Antimicrobial Prophylaxis

Published On 2016-08-23 10:24 GMT   |   Update On 2016-08-23 10:24 GMT

In 2016 National Centre For Disease Control, Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India came out with National Treatment Guidelines for Antimicrobial Use in Infectious Diseases.



Following are major recommendation for


Surgical Antimicrobial Prophylaxis :



  • To be administered within 1 hr before the surgical incision.

  • Single dose is recommended. Consider for second intra-operative dose in prolong surgery based on the choice of antibiotic used for prophylaxis.

  • Prophylaxis should not be given beyond surgery duration (except for cardiothoracic surgery, up to 48 hours permissible)

  • Choice of the prophylaxis should be based on the local antibiogram.













































SURGERYMEDICATION
BreastInj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Gastroduodenal & biliaryInj.Cefaperazone- Sulbactam 2gm IV stat & BD for 24hrs(maximum)
ERCPInj.Piperacillin-Tazobactum 4.5gm or Inj.Cefaperazone- Sulbactam 2gm IV stat
CardiothoracicInj.Cefuroxime 1.5gm IV stat & BD for 48hrs
Colonic surgeryInj.Cefaperazone- Sulbactam 2gm IV stat & BD for 24hrs(maximum)
Abdominal surgery (hernia)Inj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Head & Neck/ ENTInj.Cefazolin 2gm IV stat
NeurosurgeryInj.Cefazolin 2gm or Inj.Cefuroxime 1.5gm IV stat
Obstetrics& GynecologyInj.Cefuroxime 1.5gm IV stat




















OrthopaedicInj.Cefuroxime 1.5gm IV stat & BD for 24 hrs(maximum)

or

Inj.Cefazolin 2gm IV stat

Open reduction of closed fracture with internal fixation- Inj.Cefuroxime 1.5gm IV stat and q 12h or Inj.Cefazolin 2gm IV stat and q 12h for 24 hrs
TraumaInj.Cefuroxime 1.5gm IV stat and q 12h (for 24 hrs) or Inj.Ceftriaxone 2gm IV OD
Urologic proceduresAntibiotics only to patients with documented bacteriuria
Trans- rectal prostatic surgeryInj.Cefaperazone- Sulbactam 2gm IV stat

You can read the full Guideline by clicking on the following link :


http://www.ncdc.gov.in/writereaddata/linkimages/AMR_guideline7001495889.pdf

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