Clinical Infectious Diseases, cix693, https://doi.org/10.1093/cid/cix693
Azithromycin, levofloxacin, rifaximin all effective for travelers diarrhea
Travelers’ diarrhea affects anywhere from 10% to 40% of short-term international travelers and recommended treatment for it includes the combination of an antibiotic, usually a fluoroquinolone or azithromycin, and loperamide for rapid resolution of symptoms. However, adverse events, postdose nausea with high-dose azithromycin, effectiveness of single-dose rifaximin, and emerging resistance to front-line agents are evidence gaps underlying current recommendations.
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